The cancer/testis antigen MAGEC2 promotes amoeboid invasion of tumor cells by enhancing STAT3 signaling

Publication
Oncogene
Xiao Song
Xiao Song
Assistant Professor

Dr. Xiao Song is an Assistant Professor in the Department of Neuroscience at the Medical University of South Carolina and a full member of the MUSC Hollings Cancer Center. Her research focuses on understanding how RNA regulation, particularly alternative splicing, shapes glioma biology, tumor cell-state plasticity, therapeutic response, and the tumor immune microenvironment. Her laboratory integrates computational genomics, transcriptomics, RNA-targeting approaches, and functional tumor models to identify RNA-based vulnerabilities and develop new therapeutic strategies for malignant brain tumors.

Hui Tang
Hui Tang
Research Assistant Professor

Dr. Hui Tang is a Research Assistant Professor in the Department of Neuroscience at the Medical University of South Carolina. His research investigates how tumor-intrinsic and immune-cell mechanisms shape the tumor microenvironment and influence cancer progression and therapeutic response. His work integrates cancer biology, immunology, patient-derived tumor models, human iPSC-derived immune cells, molecular and cellular assays, and transcriptomic approaches to define tumor-immune interactions and identify strategies to enhance antitumor immunity.